Adrenal Weight and Ascorbic Acid Concentration in Alloxan-Injected Rats

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Abstract
The mean adrenal wt./100 g. body wt., and the adrenal ascorbic acid concn. of groups of rats approx. 3 days after subcut. or intraven. injn. of alloxan were shown to be significantly greater than the respective mean values in intact rats. The extent of adrenal ascorbic acid depletion 60 min. after subjection to an acutely stressful condition (208 mg, glucose soln. by intraven. admn.) in intact and alloxan-injected groups was practically identical; and significantly lower concn. than control values were obtained.