HORMONAL FACTORS INFLUENCING FAT DEPOSITION IN THE INTERSCAPULAR BROWN ADIPOSE TISSUE OF THE WHITE RAT1
- 1 January 1953
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 52 (1) , 57-64
- https://doi.org/10.1210/endo-52-1-57
Abstract
Thyroxine and cortisone both promote the accumulation of fat in the brown adipose tissue of intact rats and their actions appear to be synergistic. Little or no change occurred in the water and fat-free dry matter contents. In adrenalectomized animals, the response to thyroid hormone was minimal while the action of cortisone administered alone or in conjunction with thyroxine was comparable to that obtained in intact rats. The admn. of DCA caused no change in the size of the brown fat. ACTH caused a slight hypertrophy of the brown adipose tissue, characterized by increases in all three fractions studied.Keywords
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