Gingival hyperplasia in rats induced by oxodipine ‐ a calcium channel blocker
- 1 March 1990
- journal article
- research article
- Published by Wiley in Journal of Periodontal Research
- Vol. 25 (2) , 65-68
- https://doi.org/10.1111/j.1600-0765.1990.tb00893.x
Abstract
Oxodipine, a new calcium channel blocker, induced gingival hyperplasia in rats. This is the first time that a calcium channel blocker has been documented as resulting in gingival hyperplasia in rats. In contrast to diphenylhydantoin, the hyperplastic changes induced by oxodipine were not precipitated by any prior irritation. The histology consisted of purely fibroblastic proliferation without infiltrate of inflammatory cells.This publication has 14 references indexed in Scilit:
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