Reduced β-Amyloid Production and Increased Inflammatory Responses in Presenilin Conditional Knock-out Mice
Open Access
- 1 November 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (45) , 46907-46914
- https://doi.org/10.1074/jbc.m409544200
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Loss of Presenilin Function Causes Impairments of Memory and Synaptic Plasticity Followed by Age-Dependent NeurodegenerationNeuron, 2004
- Presenilins are not required for Aβ42 production in the early secretory pathwayNature Neuroscience, 2002
- Multiple Effects of Aspartate Mutant Presenilin 1 on the Processing and Trafficking of Amyloid Precursor ProteinJournal of Biological Chemistry, 2001
- APP Processing and Synaptic Plasticity in Presenilin-1 Conditional Knockout MiceNeuron, 2001
- Behavioral and Neuropathologic Changes Induced by Central Injection of Carboxyl‐Terminal Fragment of β‐Amyloid Precursor Protein in MiceJournal of Neurochemistry, 1998
- The presenilins and Alzheimer's diseaseHuman Molecular Genetics, 1997
- Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor proteinNature, 1997
- Accumulation of β-Amyloid fibrils in pancreas of transgenic miceNeurobiology of Aging, 1996
- Expression of Rat Cathepsin S in Phagocytic CellsJournal of Biological Chemistry, 1996
- β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activityCell, 1995