Inhibition of Histaminase Release from Human Granulocytes by Products of Histaminase Activity
- 5 October 1979
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 206 (4414) , 77-78
- https://doi.org/10.1126/science.113872
Abstract
Imidazoleacetic acid, a product of the action of histaminase (E.C. 1.4.3.6) on histamine, inhibits specific release of histaminase from human peripheral blood granulocytes with an inhibition constant between 5 X 10(-9)M and 1 X 10(-8)M. Hence, modulation of enzyme release is indirectly mediated by the activity of the enzyme.Keywords
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