Failure of acetylcholine to release histamine from rat mast cells
- 1 April 1980
- journal article
- research article
- Published by Springer Nature in Inflammation Research
- Vol. 10 (1-2) , 1-3
- https://doi.org/10.1007/bf02024170
Abstract
The action of various salts of acetylcholine on isolated mast cells from Wistar and F1 hybrids of Wistar and August rats was investigated. None of the acetylcholine salts within the concentration range 10−12 M to 10−2 M was able to release histamine either from Wistar or from hybrid mast cells. Compound 48/80, used as a control, was active in both cases. The results obtained are in opposition to some recent reports. The possible reasons for these contradictions are discussed.This publication has 12 references indexed in Scilit:
- Release of histamine from rat mast cells by acetylcholineNature, 1978
- Modulation of the spontaneous histamine release by adrenergic and cholinergic drugsInflammation Research, 1978
- The mechanism of histamine release induced by the ionophore X537A from isolated rat mast cells: 1. Significance of Monovalent Cations, Calcium, Metabolic Energy and TemperatureActa Physiologica Scandinavica, 1978
- Immunologic Release of Chemical Mediators from Human TissuesAnnual Review of Pharmacology, 1975
- Immunologic Release of Chemical Mediators from Human Nasal PolypsNew England Journal of Medicine, 1973
- Effects of known and suspected neurotransmitter substances and of some nucleotides on isolated mast cellsCellular and Molecular Life Sciences, 1972
- Storage of 5‐Hydroxytryptamine in Rat Mast Cells. Evidence for an Ionic Binding to Carboxyl Groups in a Granule Heparin‐Protein ComplexActa Physiologica Scandinavica, 1972
- Studies on the Time Course of Histamine Release and Morphological Changes Induced by Histamine Liberators in Rat Peritoneal Mast CellsActa Physiologica Scandinavica, 1967
- Mode of Storage of Histamine in Mast CellsActa Physiologica Scandinavica, 1966
- A METHOD FOR THE FLUOROMETRIC ASSAY OF HISTAMINE IN TISSUES1959