Über das glykolytische Vermögen verschiedener Organe und seine Abhängigkeit vom Co-Fermentgehalt.

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Abstract
Changes in the glycolysis of freshly cut tissues of different organs caused by the addition of purified coferment from rat tumors were investigated. Measurements with and without the addition of coferment permitted an estimation of original coferment content in comparison with the rest of the glycolytic mechanism of the given organ; the amount of glycolysis attained by addition of optimal amounts of coferment gave measure of the remaining part of the ferment with the exception of the coferment. All the organs investigated as well as the tumors showed increased glycolysis; the increases, however, varied in amount. The extent of glycolysis of mouse carcinoma was increased only slightly and to a value not larger than the highest of Warburg''s observed lactic acid quotients of 0.15X (mgm. lactic acid)/(mgm. dry wt. Xhrs.). The glycolysis of gray brain substance increased from 0.04[long dash]0.08 to 0.09-0.13; that of kidney from 0.01-0.02 to 0.08-0.09. Spleen, liver, and muscle possessed lactic acid quotients of 0.004-0.018 which were increased 2-3 times by adding coferment. The glycolysis of blood, 0.08-0.11 (mgm. lactic acid)/(mgm. blood Xhrs.), was approximately doubled by adding coferment. These experiments showed that the content of glycolytic ferment varied in different parts of the organism, but was continually so adjusted that coferment formed the limiting factor for glycolysis.

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