Rat liver BiP/GRP78 is down‐regulated by a peroxisome‐proliferator, clofibrate
- 17 August 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 308 (2) , 207-210
- https://doi.org/10.1016/0014-5793(92)81275-q
Abstract
Administration of clofibrate in rat results in down‐regulation of several liver proteins and a vast induction of peroxisomal proteins. One protein was identified as BiP/GRP78 using antibodies and cDNA cloning. The level of mRNA was reduced by the drug.Keywords
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