Applications of dioxetane chemiluminescent probes to molecular biology
- 1 November 1990
- journal article
- research article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 62 (21) , 2258-2270
- https://doi.org/10.1021/ac00220a003
Abstract
DNA probes and synthetic oligonucleotides in general present one of the key tools in modern molecular biology research and increasingly also in commercial applications. Along with the many applications that have been developed for and with DNA probes, faster and more sensitive detection methods are being developed. One of the most promising recent developments presents a method based on enzymatically triggered chemiluminescence. Details of this chemistry along with applications in molecular biology and immunology will be discussed and compared to conventional methods.This publication has 29 references indexed in Scilit:
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