Mucopolysaccharides in synovial fluid. Effect of aspirin and indomethacin on hyaluronic acid.

Abstract
Hyaluronic acid in synovial fluid is depoly-merized in untreated inflammatory arthritis irrespective of the etiology. A biochemical method of in vivo assessment of anti-inflammatory drugs is discussed. This method has been used to demonstrate an anti-inflammatory effect of indomethacin and aspirin in man.

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