A review of the role of 70 kDa heat shock proteins in protein translocation across membranes
- 1 October 1990
- journal article
- review article
- Published by Springer Nature in Antonie van Leeuwenhoek
- Vol. 58 (3) , 137-146
- https://doi.org/10.1007/bf00548924
Abstract
The compartmentalization of essential hsp70 proteins indicates that hsp70s carry out crucial functions in several compartments of the cell. The use of conditional mutants has allowed study of the cellular processes that require hsp70 function. For efficient translocation of proteins across membranes hsp70s are required in the cytoplasm, as well as in the matrix of mitochondria and in the lumen of the endoplasmic reticulum.Keywords
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