Heterophile Hanganutziu-Deicher Antigen in Ganglioside Fractions of Human Melanoma Tissues
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 85 (3) , 381-383
- https://doi.org/10.1159/000234536
Abstract
Gangliosides were purified from melanoma tissue extracts obtained from 5 patients. GM3 and GD3 were identified as the major components in ganglioside fractions of the melanoma tissues. Following thin-layer chromatography, enzyme immunostaining with Hanganutziu-Deicher (H-D) antigen-specific chicken antisera demonstrated the presence of NeuGc-neolactotetraosylceramide(H-D5) and NeuGc-lacto-N-norhexaosylceramide (H-D7) in all 5 melanoma extracts.Keywords
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