The immediate product of brain-tissue decarboxylations
- 1 October 1962
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 85 (1) , 110-112
- https://doi.org/10.1042/bj0850110
Abstract
The application of a method to tissue homogenates producing CO2 at physiological rates, that distinguishes between CO2 and NCO2 as the immediate respiratory product, is presented. The results fit the theoretical criteria for the immediate production of CO2 as the decarboxylation product in mouse-brain homogenates. The significance of this finding in the interpretation and theory of the anticonvulsant effect of carbonic-anhydrase inhibitors is discussed.Keywords
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