AN AUTOPSY CASE OF RELAPSING POLYCHONDRITIS

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Abstract
The first autopsy case of relapsing polychondritis in Japan in a 25‐year‐ old woman was presented. The disease began first in the nasal septum, and gradually involved both external ears and the respiratory tract.The pathological changes were exclusively confined to the cartilaginous tissues. The extent and severity of the lesions were apparently different from cartilage to cartilage. The changes consisted essentially of alterations and disappearance of cartilaginous tissues with acute chondritis and perichondritis accompanied by various inflammatory cell infiltrations. Leucocytic reactions in these lesions seemed to be more intensive than those in cases reported before. The initial change was supposed to be loss of basophilia in the matrix, later developing to chondrocyte alterations and marginal erosion of the cartilage. ACTA PATH. JAP. 18: 185–195, 1968.

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