Mouse Monoclonal Antibodies with Anti-A, Anti-B and Anti-A,B Specificities; Some Superior to Human Polyclonal ABO Reagents
- 1 April 1984
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 46 (4) , 185-193
- https://doi.org/10.1111/j.1423-0410.1984.tb00074.x
Abstract
A series of fusions using mouse myeloma cells and spleen cells from mice immunized with blood group substances or human red cells was performed with the aim of obtaining ABO antibodies suitable for routine blood grouping. Seven strongly agglutinating antibodies against antigens in the ABO system were obtained from 18 fusions. These antibodies were tested extensively in manual and automated routines, and 6 of them were found to be as good as or better than commercial polyclonal test sera of human origin.This publication has 14 references indexed in Scilit:
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