Lipase-Mediated Resolutions of 1-Aryl-3-Buten-1-ols
- 1 April 1997
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 27 (7) , 1217-1222
- https://doi.org/10.1080/00397919708003359
Abstract
Racemic mixtures of 1-aryl-3-buten-1-ols were separated with high enantioselectivity by a lipase-mediated acetylation with vinyl acetate. The effects of the nature, position, and spatial requirements of the phenyl-ring substituents on the separation efficacy were investigated.Keywords
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