Human B‐blast specific target determinants in CML: a family study
- 1 March 1982
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 19 (3) , 222-229
- https://doi.org/10.1111/j.1399-0039.1982.tb01443.x
Abstract
Human B blast specific target determinants, selectively identified on pokeweed mitogen stimulated purified B lymphoblasts by in vitro generated cytotoxic T lymphocytes, have previously been studied in the population and showed association to and inclusion of HLA-DR gene products. This report indicates that B blast specific target determinants apparently are products of genes which, in a codominant mendelain way, segregate with the HLA haplotypes in 4 selected Dutch families. Tests of families with HLA-B/D, DR and HLA-D, DR/GLO recombinations show that human B blast specific target determinants are coded from loci (locus) in the HLA-D region, between HLA-B and GLO.This publication has 10 references indexed in Scilit:
- Cell Mediated Lympholysis in Man: An Attempt to Type with Cytotoxic LymphocytesTissue Antigens, 2008
- HLA-linked B cell alloantigens of a new segregant series: Population and family studies of the SB antigensHuman Immunology, 1980
- A New Determinant, Defined by PLT, Coded for in the HLA Region and Apparently Independent of the HLA‐D and DR LociTissue Antigens, 1980
- Human B‐Blast Specific Target Determinants in CML: A Methodological StudyTissue Antigens, 1980
- Generation of HLA‐D Specific Primed Lymphocyte Typing (PLT) Cells and Cross‐Reactions of PLT‐Cells Primed with Homozygous Typing CellsTissue Antigens, 1980
- CELL-MEDIATED LYMPHOCYTOTOXICITY DIRECTED AGAINST HLA-D GENE PRODUCTSTransplantation, 1979
- Immunological dissection of human Ia molecules.The Journal of Experimental Medicine, 1978
- A WEAK HUMAN MLR LOCUS MAPPING AT THE RIGHT OF A CROSSING‐OVER BETWEEN HLA‐D, Bf AND GLOInternational Journal of Immunogenetics, 1978
- Cell Mediated Lympholysis in Man. The Impact of HLA‐C AntigensTissue Antigens, 1976
- Cell Mediated Lympholysis in Man. Occurrence of Unexpected, HL‐A (LA and FOUR) Irrelevant LympholysisTissue Antigens, 1974