N,N-6-bis-[2-(3,4-dihydroxybenzyl)pyrrolidinyl]hexane, a potent, selective, orally active dopamine analog with hypotensive and diuretic activity
- 19 October 1995
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 5 (20) , 2371-2376
- https://doi.org/10.1016/0960-894x(95)00413-n
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- Synthesis and Pharmacological Evaluation of N,N-di-n-Propyldopamine Congeners Containing Phenolic BioisosteresJournal of Pharmaceutical Sciences, 1987
- Hemodynamic Effects of Selective Dopamine Receptor Agonists in the Rat and DogClinical and Experimental Hypertension. Part A: Theory and Practice, 1987
- Syntheses and in vitro evaluation of 4-(2-aminoethyl)-2(3H)-indolones and related compounds as peripheral prejunctional dopamine receptor agonistsJournal of Medicinal Chemistry, 1986
- Dopamine receptor agonist activity of some 5-(2-aminoethyl)carbostyril derivativesJournal of Medicinal Chemistry, 1985
- Evidence for the existence of vascular alpha 2-adrenergic receptors in humans.Hypertension, 1984
- 6-Hydroxy-4-[2-di-n-propylaminoethyl]indole: synthesis and dopaminergic actionsJournal of Medicinal Chemistry, 1984
- 4-(Aminoalkyl)-7-hydroxy-2(3H)-indolones, a novel class of potent presynaptic dopamine receptor agonistsJournal of Medicinal Chemistry, 1983
- Modification of cardiovascular actions of 2-amino-5,6-dihydroxytetralin by N,N-Di-n-propyl substitutionEuropean Journal of Pharmacology, 1982
- Proposed dopaminergic pharmacophore of lergotrile, pergolide, and related ergot alkaloid derivativesJournal of Medicinal Chemistry, 1981
- Reduction of bovine pulmonary hypertension by normoxia, verapamil and hexaprenalineCellular and Molecular Life Sciences, 1977