In vitroandIn vivoprotein synthesis inCandida albicans
- 1 January 1970
- journal article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 8 (3) , 177-188
- https://doi.org/10.1080/00362177085190861
Abstract
Polysomal particles of various sizes with at least, 5 ribosomes were isolated from growing cells of a strain of Candida albicans. Single ribosomes were associated with messenger RNA to form polysomes and many of them were bound to cytoplasmic membranes. Evidence for polysomes to synthesize protein in vitro and in vivo was provided. The characteristics of the present sub-cellular protein-synthesizing system from C. albicans appeared essentially similar to those of Saccharomyces reported earlier but with the requirement of a higher concentration of magnesium ions for optimal incorporation of phenylalanine directed by native messengers or polyuridylic acid.Keywords
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