LOSS OF HLA‐A,B,C IN COLORECTAL CARCINOMA IS RELATED TO THE DEGREE OF DE‐DIFFERENTIATION
- 2 April 1986
- journal article
- Published by Wiley in International Journal of Immunogenetics
- Vol. 13 (2-3) , 195-200
- https://doi.org/10.1111/j.1744-313x.1986.tb01101.x
Abstract
By means of immunoperoxidase staining of frozen sections 100 primary colorectal carcinomas and 19 metastases were studied for the expression of HLA-A,B,C antigens. A substantial number of the tumours showed a deficient class I expression. The loss of HLA-A,B,C correlated with the degree of de-differentiation.Keywords
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