DOXORUBICIN IN PREGNANCY - POSSIBLE TRANS-PLACENTAL PASSAGE
- 1 January 1983
- journal article
- research article
- Vol. 67 (9) , 773-777
Abstract
Two pregnant women with lymphoproliferative disorders [acute lymphoblastic leukemia and lymphadenopathy] were treated with doxorubicin-containing regimens. Both patients delivered shortly after a dose of doxorubicin. One child was healthy and the other was stillborn. Measurements of anthracycline levels in placental, cord and fetal tissues by high-performance liquid chromatography suggest that doxorubicin may be transported across the placenta.This publication has 14 references indexed in Scilit:
- Doxorubicin in the First Trimester of PregnancyAnnals of Internal Medicine, 1981
- Normal Infant after Treatment of Acute Myeloid Leukaemia in Pregnancy with DaunorubicinAustralian and New Zealand Journal of Medicine, 1978
- Sister chromatid exchanges and chromosomal aberrations induced in human lymphocytes by the cytostatic drug adriamycin in vivo and in vitroMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1978
- MUTAGENICITY OF ACLACINOMYCIN-A AND DAUNOMYCIN DERIVATIVES1978
- MAMMARY-TUMORS INDUCED IN RATS BY ADRIAMYCIN AND DAUNOMYCIN1978
- Successful treatment of acute leukemia during pregnancy. Combination therapy in the third trimesterArchives of internal medicine (1960), 1977
- Successful pregnancy in acute monocytic leukaemiaBritish Journal of Cancer, 1976
- TUMORIGENICITY INVIVO AND INDUCTION OF MALIGNANT TRANSFORMATION AND MUTAGENESIS IN CELL-CULTURES BY ADRIAMYCIN AND DAUNOMYCIN1976
- Fetal Effects During Cyclophosphamide and Irradiation TherapyAnnals of Internal Medicine, 1971
- Methotrexate-induced congenital malformationsThe Journal of Pediatrics, 1968