Liver Disease in Pregnancy

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Abstract
Liver disease is a rare complication of pregnancy, but when it occurs it may do so in a dramatic and tragic fashion for both mother and infant. Diseases such as acute fatty liver of pregnancy (AFLP) may begin innocuously with mild symptoms and liver-enzyme abnormalities but, if left untreated, can progress to jaundice, liver failure, and death.Some of the normal physiologic changes of pregnancy can mimic abnormalities associated with liver disease. In an uncomplicated pregnancy, many laboratory-test results may appear abnormal according to standards derived from a nonpregnant population. Serum albumin concentrations decrease from a mean of 4.2 g . . .

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