Molecular analysis of a cell lineage
- 31 March 1983
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 302 (5910) , 670-676
- https://doi.org/10.1038/302670a0
Abstract
Mating type interconversion has a precise lineage which serves to minimize the time taken for yeast cells to achieve the diploid state. The HO gene either encodes or regulates an endonuclease which initiates the interconversion process. Expression of this gene is switched on during the G1 phase of mother cells and not at all during the cell cycle of their daughters. This behaviour can explain what is known about the lineage.Keywords
This publication has 21 references indexed in Scilit:
- MOLECULAR GENETICS OF YEAST MATING TYPEAnnual Review of Genetics, 1982
- Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locusCell, 1982
- The regulation of yeast mating-type chromatin structure by SIR: An action at a distance affecting both transcription and transpositionCell, 1982
- A position-effect control for gene transposition: State of expression of yeast mating-type genes affects their ability to switchCell, 1981
- Cell-cycle regulation of yeast histone mRNACell, 1981
- Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.Proceedings of the National Academy of Sciences, 1980
- Association of the 2-micron DNA plasmid with yeast folded chromosomes.Proceedings of the National Academy of Sciences, 1980
- Asymmetry and directionality in production of new cell types during clonal growth: the switching pattern of homothallic yeastCell, 1979
- Folded chromosomes in non-cycling yeast cellsChromosoma, 1978
- Physiology of Mating in Three YeastsPublished by Elsevier ,1977