BRIEF REPORT: Absence of Hemoglobin A in a Double Heterozygote for F-Thalassemia and Hemoglobin S
Open Access
- 1 December 1967
- journal article
- research article
- Published by American Society of Hematology in Blood
- Vol. 30 (6) , 772-776
- https://doi.org/10.1182/blood.v30.6.772.772
Abstract
An adult with minor hematologic abnormalities and hemoglobin electrophoretic pattern characterized by large amounts of hemoglobins S and F together with absent hemoglobin A, was shown to be doubly heterozygous for F-thalassemia and hemoglobin S. Absence of Hb A in this double heterozygote provides further evidence that in F-thalassemia the suppression of the β-chains in cis position is complete.This publication has 5 references indexed in Scilit:
- Absence of Cis Delta Chain Synthesis in (δ β) Thalassemia (F-thalassemia)Blood, 1966
- Studies on the heterogeneity of hemoglobinJournal of Chromatography A, 1965
- Hereditary Persistence of Fetal Hemoglobin in Greece. A Study and a ComparisonBlood, 1964
- Thalassemia TraitNew England Journal of Medicine, 1964
- Sickle Cell Haemoglobin and two Types of Thalassaemia in the Same FamilyActa Haematologica, 1962