CORTICOSTEROID SECRETION FOLLOWING CAVAL CONSTRICTION IN DOGS WITH ISOLATED PITUITARIES1
- 1 February 1961
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 68 (2) , 226-231
- https://doi.org/10.1210/endo-68-2-226
Abstract
The output per minute of 17-hydroxycorticostcroids was measured before and after partial thoracic inferior vena caval constriction in normal dogs and those with brain removal and isolated pituitaries. The “resting” control 17-hydroxycorticosteroid output was higher in dogs with brain removal than in normal animals. Both groups of dogs demonstrated a significant increase in corticosteroid output following caval constriction. It is concluded that partial constriction of the thoracic inferior vena cava is a strong stimulus to ACTH release.Keywords
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