Further studies on the synthesis of quinazolines from 2-fluorobenzonitriles
- 1 August 1991
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 28 (5) , 1357-1363
- https://doi.org/10.1002/jhet.5570280530
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acidBiochemical Pharmacology, 1991
- Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C-2 positionJournal of Medicinal Chemistry, 1990
- Synthesis of 5‐trifluoromethyl‐5,8‐dideazafolic acid and 5‐trifluoromethyl‐5,8‐dideazaisofolic acidJournal of Heterocyclic Chemistry, 1990
- Synthesis and preliminary biological evaluation of 5-fluoro-5,8-dideazaisoaminopterinJournal of Heterocyclic Chemistry, 1990
- Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorinBiochemical Pharmacology, 1989
- Inhibition of mammalian folylpolyglutamate synthetase and human dihydrofolate reductase by 5,8-dideaza analogs of folic acid and aminopterin bearing a terminal L-ornithineJournal of Medicinal Chemistry, 1989
- Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potencyJournal of Medicinal Chemistry, 1989
- Direct synthesis of 2,4‐diaminoquinazolines from 2‐fluorobenzonitrilesJournal of Heterocyclic Chemistry, 1988
- Quinazolines. VI. Synthesis of 2,4-diaminoquinazolines from anthranilonitrilesJournal of Medicinal Chemistry, 1970
- Syntheses of 4-Fluoro- and 4-Aminoquinazoline Derivatives and Relationship between Reactivities and Frontier-electron Densities at C4 : Electronic Properties of N-Heteroaromatics. XXYAKUGAKU ZASSHI, 1968