Biosynthesis of chrysomycins A and B origin of the chromophore.
- 1 January 1985
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 38 (2) , 242-248
- https://doi.org/10.7164/antibiotics.38.242
Abstract
The biosynthetic origin of the C atoms in the chromophores of chrysomycins A and B was investigated in feeding experiments using 13C labeled acetates and propionate. A biosynthetic scheme is proposed involving the condensation and rearrangement of a decaketide intermediate which contains propionate (chrysomycin A) or acetate (chrysomycin B) as the chain initiator. [Streptomyces flaveolus was used.].This publication has 6 references indexed in Scilit:
- Structure and stereochemistry of toromycin; studies of its acid-catalyzed rearrangementTetrahedron, 1983
- Gilvocarcins,new antitumor antibiotics 5. Biosynthesis of gilvocarcins: Incorporation of 13C-labeled compounds into gilvocarcin aglycones.The Journal of Antibiotics, 1983
- Ravidomycin (AY-25,545),a new antitumor antibiotic.The Journal of Antibiotics, 1983
- Antitumor agents from Streptomyces anandii: gilvocarcins V, M and E.The Journal of Antibiotics, 1981
- Toromycin, a New Antibiotic Produced byStreptomyces collinussubsp.albescenssubsp. novAgricultural and Biological Chemistry, 1980
- PHYSICOCHEMICAL CHARACTERISTICS OF VIRENOMYCIN, A NEW ANTI-TUMOR ANTIBIOTIC1977