Effect of Thyroidectomy and Adrenalectomy on the Physio-chemical Status of Rat Testes

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Abstract
The influence of thyroid and adrenal hormones on the testicular biochemical activities and their role in the mechanism of male gonadal function were reported. Thyroidectomized and adrenalectomized animals revealed that thyroid deficiency caused a decrease in acid phosphatase activities, increase in cholesterol and GOT [glutamic oxaloacetic acid] activities, where as hypoadrenalism had, to some extent, opposite effects compared to intact controls. These findings point out that thyroid hormones are very important for and regulate male reproduction by maintaining gonadal biochemical homeostasis and adjuvating the action of gonadotrophins for steroidogenesis.