Mevalonate Promotes the Growth of Tumors Derived from Human Cancer Cells in Vivo and Stimulates Proliferation in Vitro with Enhanced Cyclin-dependent Kinase-2 Activity
Open Access
- 1 August 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (32) , 33079-33084
- https://doi.org/10.1074/jbc.m400732200
Abstract
No abstract availableKeywords
This publication has 60 references indexed in Scilit:
- Treatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in femalesBiochemical Pharmacology, 2003
- Inhibition of N-methyl-N-nitrosourea- and 7,12-dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by dietary cholesterol is independent of Ha-ras mutationsCarcinogenesis: Integrative Cancer Research, 2000
- Dietary cholesterol inhibits the development of aberrant crypt foci in the colonNutrition and Cancer, 1996
- SHORT COMMUNICATION: Inhibition of rat mammary tumorigenesis by dietary cholesterolCarcinogenesis: Integrative Cancer Research, 1996
- Importance of mevalonate‐derived products in the control of HMG‐CoA reductase activity and growth of human lung adenocarcinoma cell line a549International Journal of Cancer, 1993
- Regulation of the mevalonate pathwayNature, 1990
- p21ras is modified by a farnesyl isoprenoid.Proceedings of the National Academy of Sciences, 1989
- Lipid Composition and De Novo Cholesterogenesis in Normal and Neoplastic Rat Mammary TissuesJNCI Journal of the National Cancer Institute, 1988
- Cholestyramine promotes 7,12-dimethylbenzanthracene induced mammary cancer in Wistar ratsBritish Journal of Cancer, 1987
- Essential role for mevalonate synthesis in DNA replicationProceedings of the National Academy of Sciences, 1979