Hb Aztec or α762Met → Thrβ2Detection of a Silent Mutant by High Performance Liquid Chromatography
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Hemoglobin
- Vol. 9 (4) , 325-332
- https://doi.org/10.3109/03630268508997008
Abstract
High performance liquid chromatography has detected 14 abnormal hematological states in 600 randomly selected samples of blood. Two of these are silent mutations which are not apparent from chromatographic or electrophoretic examination. One of these has the substitution α76 (EF5) Met → Thr and has been named Hb Aztec. The variant was first detected in a 9-day-old baby girl who had inherited it from her mother. This abnormal hemoglobin has no obviously deleterious effect or hematological status or health.This publication has 8 references indexed in Scilit:
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