Abstract
One hundred young male outpatients with coronary disease who were under dietary management with a 28% fat diet were group-matched to a non-dietary-managed group in regard to age, age at infarction, number of infarctions, prevalence of hypertension, degree of angina, and value of serum cholesterol, among other factors. The diet-managed group experienced a significant reduction in serum cholesterol value, while the non-dietary-managed group did not. No significant differences were noted between the 2 groups in levels for serum total lipids, phospho-lipids, and triglycerides. Under the experimental conditions employed, the degree of unsaturation of the diet did not appear to influence serum cholesterol value or mortality. The non-dietary-managed group had a 160% higher recurrent infarction rate and a 233% higher mortality rate than did the dietary-managed group during the 1st 5 years of observation.