Carcinogen-Induced Immune Depression: Absence in Mice Resistant to Chemical Oncogenesis
- 31 October 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3905) , 620-621
- https://doi.org/10.1126/science.166.3905.620
Abstract
Administration of 3-methylcholanthrene 6 days before antigenic challenge depressed the immune response to sheep red cells in young adult mice (C3Hf/Bi strain) sensitive to the oncogenic effect of the drug (100 percent local tumors 240 days after carcinogen). The drug was not immunodepressant in the I strain, which is relatively resistant to its carcinogenic effect (11 percent local tumors 240 days after carcinogen).Keywords
This publication has 12 references indexed in Scilit:
- Immunotherapy of Cancer: Experiments with Primary Tumours and Syngeneic Tumour GraftsPublished by S. Karger AG ,2015
- Immune reactivity prior to development of thymic lymphoma in C57BL miceInternational Journal of Cancer, 1967
- Tumor AntigensAnnual Review of Microbiology, 1966
- Prolonged Immunosuppression and Tumor Induction by a Chemical Carcinogen Injected at BirthScience, 1966
- IMMUNOLOGICAL FACTORS IN THE PROCESS OF CARCINOGENESISBritish Medical Bulletin, 1964
- Immunology of Experimental TumorsAnnual Review of Medicine, 1964
- ANTIGENIC PROPERTIES OF CHEMICALLY INDUCED TUMORS*Annals of the New York Academy of Sciences, 1962
- The Antigenic Structure of TumorsPublished by Elsevier ,1961
- Reduced Antibody Titers in Mice Treated with Carcinogenic and Cancer Chemotherapeutic AgentsExperimental Biology and Medicine, 1952
- Immunochemical Changes in Chicken Serum During Development of Rous SarcomaScience, 1951