PERIPHERAL VASCULAR H-2 RECEPTORS TO HISTAMINE

  • 1 January 1979
    • journal article
    • research article
    • Vol. 6  (3) , 213-221
Abstract
The development of 2 different types of antagonists to the many actions of histamine permitted exploration of vascular receptors to the amine. Certain cautions are necessary to avoid inaccurate conclusions in such studies. A literature review revealed that both H1 and H2 receptors to histamine are widely distributed in the [renal, gastric intestinal, hepatic and regional] circulation [in rabbits, cats and dogs]. In a given regional vasculature discrete actions of each receptor may be evident.