Effect of Saturated and Unsaturated Fats on the Concentration of Serum Cholesterol and Experimental Atherosclerosis

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Abstract
The feeding of a diet rich in unsaturated fats to rabbits produced no significant alteration of the serum cholesterol level, while the feeding of a diet rich in saturated fats produced an elevation of the serum cholesterol without the development of experimental atherosclerosis. The addition of unsaturated fats to a diet rich in cholesterol failed to prevent hypercholesterolemia and experimental atherosclerosis in rabbits.

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