The utility of superparamagnetic contrast agents in MRI: theoretical consideration and applications in the cardiovascular system
Open Access
- 3 November 2004
- journal article
- review article
- Published by Wiley in NMR in Biomedicine
- Vol. 17 (7) , 465-477
- https://doi.org/10.1002/nbm.904
Abstract
This review will discuss the in vivo physical chemical relaxation properties of superparamagnetic iron oxide particles. Various parameters such as size, magnetization, compartmentalization and water exchange effects and how these alter the behavior of the iron oxide particles in an in vitro vs an in vivo situation with special reference to the cardiovascular system will be exemplified. Furthermore, applications using iron oxide particles for vascular, perfusion and viability imaging as well as assessment of the inflammatory status of a given tissue will be discussed. Copyright © 2004 John Wiley & Sons, Ltd.Keywords
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