The Use of 75Se‐Methionin for the in vivo Study of Platelet Kinetics
- 1 December 1969
- journal article
- Published by Wiley in Scandinavian Journal of Haematology
- Vol. 6 (6) , 395-401
- https://doi.org/10.1111/j.1600-0609.1969.tb01833.x
Abstract
Platelet kinetics were studied using 75Se‐methionin as an in vivo tracer in normal and aplasic rats and in normal man and in patients suffering from bone marrow inadequacy, thrombocytosis, thrombocytopenia due to hyperdestruction.Results are compared with those obtained with 51Cr‐labelling.The method is found useful to measure both platelet production and autologous platelet life span in thrombocytopenic patients.Keywords
This publication has 13 references indexed in Scilit:
- Kinetics of thrombopoiesisJournal of Clinical Investigation, 1968
- Platelet Economy (Platelet Survival and Turnover)*British Journal of Haematology, 1966
- Radioisotope Scanning of the Pancreas with Selenomethionine (Se73)Radiology, 1964
- Survival of Radiochromium-labeled Platelets in ThrombocytopeniasBlood, 1963
- DETERMINATION OF HUMAN PLATELET SURVIVAL UTILIZING C14-LABELED SEROTONIN*Journal of Clinical Investigation, 1961
- Labelling of Blood Platelets of the Pig with [35S]SulphateBritish Journal of Haematology, 1961
- Chemical Studies of Mucopolysaccharides of Rat Blood PlateletsExperimental Biology and Medicine, 1958
- Survival of Blood Platelets Labeled with Chromium5112Journal of Clinical Investigation, 1958
- Uptake of Radioactive Sulfate by Elements of the Blood and the Bone Marrow of RatsAmerican Journal of Physiology-Legacy Content, 1955
- STUDIES IN METHIONINE METABOLISM. III. THE FATE OF INTRAVENOUSLY ADMINISTERED S35-LABELED-METHIONINE IN NORMAL ADULT MALES, IN PATIENTS WITH CHRONIC HEPATIC DISEASE, “IDIOPATHIC” HYPOPROTEINEMIA AND CUSHING'S SYNDROME 1Journal of Clinical Investigation, 1950