Hypergonadotrophic hypogonadism with preserved fertility — A new syndrome?
- 1 November 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 95 (3) , 388-392
- https://doi.org/10.1530/acta.0.0950388
Abstract
: It has been claimed that a follicle-stimulating hormone (FSH) level above approximately 8 μg/l indicates ovarian failure without functioning follicles in the ovaries. Exceptional cases with elevated FSH levels and a preserved follicular apparatus in the ovaries have been published. But in none of these cases has pregnancy been reported. This paper presents a case, which, to the best of our knowledge, is the first case in which pregnancy occurred in a patient with persistent hypergonadotrophic hypogonadism and a histologically verified normal number of primordial ovarian follicles. The finding of menopausal levels of plasma FSH is not sufficient by itself to exclude the existence of functioning follicles in the ovaries in an amenorrhoeic patient.This publication has 7 references indexed in Scilit:
- HORMONAL AND ULTRASTRUCTURAL OBSERVATIONS IN A CASE OF RESISTANT OVARY SYNDROMEActa Endocrinologica, 1978
- OESTROGEN TREATMENT AND SUBSEQUENT PREGNANCY IN TWO PATIENTS WITH SEVERE HYPERGONADOTROPHIC OVARIAN FAILUREActa Endocrinologica, 1978
- Pregnancy Following the “Insensitive Ovary Syndrome”Fertility and Sterility, 1977
- The “Gonadotropin-Resistant Ovary” Syndrome as a Cause of Secondary Amenorrhea and InfertilityFertility and Sterility, 1977
- PITUITARY GONADOTROPHIN SECRETION DURING THE FIRST WEEKS OF PREGNANCYActa Endocrinologica, 1977
- Spontaneous Pregnancy In Association With Hypergonadotropic Ovarian FailureFertility and Sterility, 1977
- PRODUCTION OF ANTISERA AGAINST HIGHLY PURIFIED HUMAN FOLLICLE-STIMULATING HORMONE, LUTEINIZING HORMONE AND THYROID-STIMULATING HORMONEJournal of Endocrinology, 1976