Antiserum to Immunoglobulin A: Inhibition of Cell-Mediated Demyelination in Tissue Culture

1 July 1966

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 153 (3731) , 75-76
https://doi.org/10.1126/science.153.3731.75

Abstract

Lymph node cells from rats immunized with sciatic nerve in Freund's adjuvant demyelinate trigeminal ganglion cultures. Rabbit antiserum to rat immunoglobulin A blocks this cytodestructive event. The antiserum may act by combining with IgA on the lymphoid cell surface, preventing the interaction of cell-bound antibody and tissue anitigen.

This publication has 16 references indexed in Scilit:

The development and maintenance of myelinated tissue cultures of rat trigeminal ganglion
Journal of Anatomy, 1966
Immunoglobulin A Production in Ataxia Telangiectasia
Science, 1965
STUDIES ON RABBIT LYMPHOCYTES IN VITRO
The Journal of Experimental Medicine, 1965
COMPOSITIONAL STUDIES OF EXTRATERRESTRIAL PARTICLES
Annals of the New York Academy of Sciences, 1964
ATAXIA-TELANGIECTASIA ITS ASSOCIATION WITH A DEFECTIVE THYMUS, IMMUNOLOGICAL-DEFICIENCY DISEASE, AND MALIGNANCY
The Lancet, 1964
Role of the Thymus in Immune Reactions in Rats
International Archives of Allergy and Immunology, 1964
Immune Response and Mitosis of Human Peripheral Blood Lymphocytes in vitro
Science, 1963
IN VITRO STUDIES OF ULCERATIVE COLITIS
The Journal of Experimental Medicine, 1963
TUBERCULIN-INDUCED MITOSIS IN PERIPHERAL BLOOD LEUCOCYTES
The Lancet, 1963
AUTOSENSITIZATION REACTION IN VITRO
The Journal of Experimental Medicine, 1962