Gene diversity in finite populations
- 1 August 1985
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 46 (1) , 107-113
- https://doi.org/10.1017/s0016672300022503
Abstract
DNA sequence comparison among homologous genes sampled at random from one or two populations allows one to estimate the ultimate amount of genetic variation maintained in a population and to construct the gene genealogy within and between populations. Moreover, if we use the finding of the molecular clock (Zuckerkandl & Pauling, 1965), it is also possible to estimate the divergence time of populations examined. Such an estimated divergence time is, however, intricately affected by samples and stochastic forces occurring in the course of evolution.Keywords
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