Liposome-bound cyclosporine: Clearance after intravitreal injection
- 1 January 1988
- journal article
- conference paper
- Published by Springer Nature in International Ophthalmology
- Vol. 12 (2) , 109-112
- https://doi.org/10.1007/bf00137135
Abstract
The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug.This publication has 14 references indexed in Scilit:
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