Blood Lipid Levels in Coronary Sclerosis as Measured By Protamine Titration, Chylomicron Index and Cholesterol Levels

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Abstract
Two groups each of 25 individuals, of both sexes and wide age variation were studied as to their blood cholesterol levels, protamine titer, and chylomicron index. One group represented "normal volunteers" and the other group individuals showing various manifestations of coronary sclerosis. There was no apparent deviation of protamine titer between the two groups nor from previously reported "normals" so it was concluded that this factor could not be used as a measure of heparin activity. The blood cholesterol levels showed only minor correlation with demonstrated sclerosis. The chylomicron index varied significantly in the experimental group as a whole and particularly in the male population. It was suggested that this latter technique may be a practical index to the effect of clearing agents on blood lipid levels.