Forced noise mechanical parameters during inspiration and expiration

Abstract
Using the forced random noise technique, three 5-min records of pressure and flow signals in 5 clinically normal nonsmoking adults were collected. Each recording was analyzed to obtain respiratory impedance spectra from data obtained during continuous sampling, midinspiration and midexpiration. Estimates of respiratory resistance, inertance and compliance were obtained by regression analysis on each impedance spectrum. Mean expiratory resistance and compliance were significantly (P < 0.01) greater than corresponding mean inspiratory values, while mean expiratory inertance was significantly (P < 0.001) less than the mean inspiratory value. Parameters from continuous sampling agreed fairly well with inspiratory resistance and inertance and with expiratory compliance. The coefficient of variation of parameters from continuous data were similar to or smaller than those from inspiratory or expiratory data. Continuous sampling appears to be an acceptable approach for collecting random noise data.