VARIABLE SUSCEPTIBILITY OF CYNOMOLGUS MONKEY KIDNEY CELLS TO THE SPECIFIC CYTOPATHIC EFFECT OF SIMIAN VIRUS 40

Abstract
The specific vacuolation was found in the cytoplasm of some batches of cynomolgus monkey kidney cells following SV40 infection, which was indistinguishable from that observed in African green monkey kidney cells. But the other batches of the cells examined did not show any such cytopathic effect. Both types of the cynomolgus monkey kidney cell cultures supported equally a full growth of SV40. The susceptibility to SV40-vacuolation was supposed to be one of the special cellular characters which might be genetically controlled.