Structure and Biological Function of Human IgD
- 1 January 1977
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 54 (1) , 1-8
- https://doi.org/10.1159/000231802
Abstract
Human peripheral lymphocytes were stimulated to incorporate 3H-thymidine when cultured with anti-.delta.. The stimulation of lymphocytes by anti-.delta. inversely correlates to PHA[phytohemagglutinin]-induced lymphocyte transformation. Lymphocytes from individuals with low serum Ig[immunoglobulin]D levels exhibited a significant response to anti-.delta., whereas those with normal or slightly elevated levels of serum IgD showed minimal stimulation. Cell surface IgD may regulate metabolic functions of lymphocytes. IgD may be a triggering receptor.This publication has 7 references indexed in Scilit:
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