The Effect of X rays on Ascorbic Acid Concentration in Plasma and in Tissues

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Abstract
The ascorbic acid has been estimated in plasma of patients under X-ray treatment, and in most cases it has been found to be below the initial level before exposure. Normal rabbits have been exposed to X rays and the blood concentration of ascorbic acid estimated. It was found that for a considerable time after exposure the level of ascorbic acid kept below the average concentration in rabbit blood. In one instance this was accompanied by an X-ray leucopenia which ran almost parallel with the rise and fall of the ascorbic acid concentration in the blood. Muscle and kidney tissues from rats were exposed in vivo to X rays and the ascorbic acid content estimated after extraction. This was found to be lower in the exposed organ as compared with the unexposed organ.

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