Expression of apoptosis-related proteins in rat with induced colitis
- 9 April 2004
- journal article
- research article
- Published by Springer Nature in International Journal of Colorectal Disease
- Vol. 19 (5) , 451-460
- https://doi.org/10.1007/s00384-004-0585-5
Abstract
Inflammatory bowel diseases (IBD) evoke a damage-repair process accompanied by the activation of apoptotic genes. Data on transglutaminase (TG) expression in apoptotic cells in inflamed colonic epithelium has not been reported, although TG cross-links proteins within typical apoptotic bodies in various cell lines. In an experimental model of colitis we investigated the expression of different markers of apoptosis related to the degree and development of colonic inflammation.Keywords
This publication has 49 references indexed in Scilit:
- Direct evidence of oxidative damage in acute and chronic phases of experimental colitis in ratsDigestive Diseases and Sciences, 1996
- Apoptosis in the Pathogenesis and Treatment of DiseaseScience, 1995
- Fas-mediated cytotoxicity by freshly isolated natural killer cells.The Journal of Experimental Medicine, 1995
- p53 expression in nitric oxide‐induced apoptosisFEBS Letters, 1994
- Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor familyCell, 1993
- Phagocyte recognition of cells undergoing apoptosisImmunology Today, 1993
- Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.The Journal of cell biology, 1992
- Serum and Tissue Transglutaminase Correlates with the Severity of Inflammation in Induced Colitis in the RatScandinavian Journal of Gastroenterology, 1992
- DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its ProgenitorsScience, 1991
- Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase actionFEBS Letters, 1989