A new type of IS1-mediated deletion
- 1 December 1981
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 184 (2) , 300-307
- https://doi.org/10.1007/bf00272921
Abstract
Genetical tests and DNA sequence analysis revealed that the mechanism of formation of IS1-induced type I and type II deletions differs. IS1-mediated type II deletions occur at the termini of the integrated element and do not remove the element. This process is independent of the cellular recA system and does not involve DNA sequence homology. Conversely, the formation of IS1-induced type I deletions differs substantially. They require recA gene product, small DNA sequence duplications and a topological arrangement of the DNA molecule to allow alignment of duplications.Keywords
This publication has 16 references indexed in Scilit:
- Three Tn10-associated excision events: Relationship to transposition and role of direct and inverted repeatsCell, 1981
- IS1-mediated DNA RearrangementsCold Spring Harbor Symposia on Quantitative Biology, 1981
- Integration of IS3 into IS2 generates a short sequence duplicationMolecular Genetics and Genomics, 1979
- Development of a system useful for studying the formation of unstable alleles of IS2Molecular Genetics and Genomics, 1979
- Genetic studies of the lac repressorJournal of Molecular Biology, 1978
- Nucleotide sequence of an insertion element, IS1.Proceedings of the National Academy of Sciences, 1978
- A new method for sequencing DNA.Proceedings of the National Academy of Sciences, 1977
- Isolation of the mini insertions IS6 and IS7 of E. coliMolecular Genetics and Genomics, 1977
- Insertion mutations in the control region of the galactose operon of E. coliMolecular Genetics and Genomics, 1972
- O o mutations in the galactose operon in E. coliMolecular Genetics and Genomics, 1967