Convergent and efficient palladium-effected synthesis of 5, 10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF)
- 1 July 1989
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 54 (15) , 3618-3624
- https://doi.org/10.1021/jo00276a023
Abstract
No abstract availableThis publication has 4 references indexed in Scilit:
- A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesisJournal of Biological Chemistry, 1989
- Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogs of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferaseJournal of Medicinal Chemistry, 1988
- Synthesis and biological properties of 5,10-dideaza-5,6,7,8-tetrahydrofolic acidArchives of Biochemistry and Biophysics, 1988
- Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterinJournal of Medicinal Chemistry, 1985