Abstract
In both cats and dogs membutal anesthesia produces a marked decrease in hematocrit (cats 26.5%, dogs 22.9%) and plasma protein conc, (cats 16%, dogs 9.3%). After splenectomy nembutal anesthesia no longer produces a greater decrease in the hematocrit value than in the plasma protein cone. The magnitude of both changes is decreased in the splenectomized animal. In dogs anesthetized with nembutal ether raises the previously lowered hematocrit and protein readings above control levels. A similar response occurs in splenectomized dogs. Neither normal nor splenectomized cats anesthetized with nembutal show any evidence of changes in blood conc, in response to ether. The same lack of reaction occurs in cats from which the abdominal sympathetic chains or the chains and both adrenals have been removed.