Species‐specific Mn2+/Mg2+ antiport from Mg2+‐loaded erythrocytes
Open Access
- 12 February 1990
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 261 (1) , 47-51
- https://doi.org/10.1016/0014-5793(90)80633-t
Abstract
Mg2+‐loaded rat erythrocytes performed Mn+/Mg2+ antiport, which was nonspecifically stimulated by anions and cations. Mn2+/Mg2+ antiport was shown to operate via the Na+Mg2+ antiporter because extracellular Na+ and Mn2+ inhibited the intracellular uptake of each other's ions competitively. Furthermore, Mn2+/Mg2+ antiport and Na+/Mg2+ antiport were identically inhibited by various amiloride derivatives. Na+/Mg2+ antiport of chicken and human erythrocytes cannot perform Mn2+/Mg2+ antiport although chicken erythrocytes took up more Mn2+ than raterythrocytes.Keywords
This publication has 6 references indexed in Scilit:
- Characterization of Mg2+ efflux from human, rat and chicken erythrocytesFEBS Letters, 1989
- Na+‐independent Mg2+ efflux from Mg2+‐loaded human erythrocytesFEBS Letters, 1989
- A one-to-one Mg2+:Mn2+ exchange in rat erythrocytes.Journal of Biological Chemistry, 1987
- Mg2+ efflux is accomplished by an amiloride-sensitive Na+Mg2+ antiportBiochemical and Biophysical Research Communications, 1985
- Regulation of intracellular magnesium by Mg2+ effluxBiochemical and Biophysical Research Communications, 1984
- Pyrazine Diuretics. II. N-Amidino-3-amino-5-substituted 6-HalopyrazinecarboxamidesJournal of Medicinal Chemistry, 1967